P301S Mutant Human Tau Transgenic Mice Manifest Early Symptoms of Human Tauopathies with Dementia and Altered Sensorimotor Gating

Tauopathies are neurodegenerative disorders characterized by the accumulation of abnormal tau protein leading to cognitive and/or motor dysfunction. To understand the relationship between tau pathology and behavioral impairments, we comprehensively assessed behavioral abnormalities in a mouse tauopa...

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Detalles Bibliográficos
Autores principales: Takeuchi, Hiroki, Iba, Michiyo, Inoue, Haruhisa, Higuchi, Makoto, Takao, Keizo, Tsukita, Kayoko, Karatsu, Yoshiko, Iwamoto, Yumiko, Miyakawa, Tsuyoshi, Suhara, Tetsuya, Trojanowski, John Q., Lee, Virginia M. -Y., Takahashi, Ryosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115982/
https://www.ncbi.nlm.nih.gov/pubmed/21698260
http://dx.doi.org/10.1371/journal.pone.0021050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115982/
https://www.ncbi.nlm.nih.gov/pubmed/21698260
http://dx.doi.org/10.1371/journal.pone.0021050

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