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Basolateral Sorting of Syntaxin 4 Is Dependent on Its N-terminal Domain and the AP1B Clathrin Adaptor, and Required for the Epithelial Cell Polarity

Generation of epithelial cell polarity requires mechanisms to sort plasma membrane proteins to the apical and basolateral domains. Sorting involves incorporation into specific vesicular carriers and subsequent fusion to the correct target membranes mediated by specific SNARE proteins. In polarized e...

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Detalles Bibliográficos
Autores principales: Reales, Elena, Sharma, Nikunj, Low, Seng Hui, Fölsch, Heike, Weimbs, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115984/
https://www.ncbi.nlm.nih.gov/pubmed/21698262
http://dx.doi.org/10.1371/journal.pone.0021181