Garlic Extract Diallyl Sulfide (DAS) Activates Nuclear Receptor CAR to Induce the Sult1e1 Gene in Mouse Liver

Constituent chemicals in garlic extract are known to induce phase I and phase II enzymes in rodent livers. Here we have utilized Car (+/+) and Car (−/−) mice to demonstrate that the nuclear xenobiotic receptor CAR regulated the induction of the estrogen sulfotransferase Sult1e1 gene by diallyl sulfi...

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Detalles Bibliográficos
Autores principales: Sueyoshi, Tatsuya, Green, William D., Vinal, Kellie, Woodrum, Tyler S., Moore, Rick, Negishi, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115993/
https://www.ncbi.nlm.nih.gov/pubmed/21698271
http://dx.doi.org/10.1371/journal.pone.0021229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115993/
https://www.ncbi.nlm.nih.gov/pubmed/21698271
http://dx.doi.org/10.1371/journal.pone.0021229

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