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PI3Kinase signaling in glioblastoma

Glioblastoma (GBM) is the most common primary tumor of the CNS in the adult. It is characterized by exponential growth and diffuse invasiveness. Among many different genetic alterations in GBM, e.g., mutations of PTEN, EGFR, p16/p19 and p53 and their impact on aberrant signaling have been thoroughly...

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Detalles Bibliográficos
Autores principales: Lino, M. M., Merlo, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116122/
https://www.ncbi.nlm.nih.gov/pubmed/21063898
http://dx.doi.org/10.1007/s11060-010-0442-z