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Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice

OBJECTIVE AND DESIGN: Cystic fibrosis transmembrane conductance regulator (CFTR) regulates infection and inflammation. In this study, we investigated whether a lack of functional CFTR in neutrophils would promote lipopolysaccharide (LPS)-induced lung inflammation and injury. MATERIALS AND METHODS: C...

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Detalles Bibliográficos
Autores principales: Su, Xiao, Looney, Mark R., Su, Hang (Emily), Lee, Jae Woo, Song, Yuanlin, Matthay, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116128/
https://www.ncbi.nlm.nih.gov/pubmed/21301926
http://dx.doi.org/10.1007/s00011-011-0313-x