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Combined Characterization of microRNA and mRNA Profiles Delineates Early Differentiation Pathways of CD133(+) and CD34(+) Hematopoietic Stem and Progenitor Cells

MicroRNAs (miRNAs) have been shown to play an important role in hematopoiesis. To elucidate the role of miRNAs in the early steps of hematopoiesis, we directly compared donor-matched CD133(+) cells with the more differentiated CD34(+)CD133(−) and CD34(−)CD133(−) cells from bone marrow on the miRNA a...

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Detalles Bibliográficos
Autores principales: Bissels, Ute, Wild, Stefan, Tomiuk, Stefan, Hafner, Markus, Scheel, Hartmut, Mihailovic, Aleksandra, Choi, Yeong-Hoon, Tuschl, Thomas, Bosio, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116150/
https://www.ncbi.nlm.nih.gov/pubmed/21394831
http://dx.doi.org/10.1002/stem.627