Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells

IL-10-producing CD4(+) type 1 regulatory T (Tr1) cells, defined based on their ability to produce high levels of IL-10 in the absence of IL-4, are major players in the induction and maintenance of peripheral tolerance. Tr1 cells inhibit T-cell responses mainly via cytokine-dependent mechanisms. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Magnani, Chiara F, Alberigo, Giada, Bacchetta, Rosa, Serafini, Giorgia, Andreani, Marco, Roncarolo, Maria Grazia, Gregori, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Immunomodulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116154/
https://www.ncbi.nlm.nih.gov/pubmed/21469116
http://dx.doi.org/10.1002/eji.201041120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116154/
https://www.ncbi.nlm.nih.gov/pubmed/21469116
http://dx.doi.org/10.1002/eji.201041120

Ejemplares similares