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Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells

IL-10-producing CD4(+) type 1 regulatory T (Tr1) cells, defined based on their ability to produce high levels of IL-10 in the absence of IL-4, are major players in the induction and maintenance of peripheral tolerance. Tr1 cells inhibit T-cell responses mainly via cytokine-dependent mechanisms. The...

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Detalles Bibliográficos
Autores principales:	Magnani, Chiara F, Alberigo, Giada, Bacchetta, Rosa, Serafini, Giorgia, Andreani, Marco, Roncarolo, Maria Grazia, Gregori, Silvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2011
Materias:	Immunomodulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116154/ https://www.ncbi.nlm.nih.gov/pubmed/21469116 http://dx.doi.org/10.1002/eji.201041120

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