Dissimilar Roles of the Four Conserved Acidic Residues in the Thermal Stability of Poly(A)-Specific Ribonuclease

Divalent metal ions are essential for the efficient catalysis and structural stability of many nucleotidyl-transfer enzymes. Poly(A)-specific ribonuclease (PARN) belongs to the DEDD superfamily of 3′-exonucleases, and the active site of PARN contains four conserved acidic amino acid residues that co...

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Detalles Bibliográficos
Autores principales: He, Guang-Jun, Liu, Wei-Feng, Yan, Yong-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116163/
https://www.ncbi.nlm.nih.gov/pubmed/21686157
http://dx.doi.org/10.3390/ijms12052901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116163/
https://www.ncbi.nlm.nih.gov/pubmed/21686157
http://dx.doi.org/10.3390/ijms12052901

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