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Mechanism of Sphingosine 1-Phosphate- and Lysophosphatidic Acid-Induced Up-Regulation of Adhesion Molecules and Eosinophil Chemoattractant in Nerve Cells

The lysophospholipids sphingosine 1-phosphate (S1P) and lysophosphatidic acid (LPA) act via G-protein coupled receptors S1P(1–5) and LPA(1–3) respectively, and are implicated in allergy. Eosinophils accumulate at innervating cholinergic nerves in asthma and adhere to nerve cells via intercellular ad...

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Detalles Bibliográficos
Autores principales: Costello, Richard W., Maloney, Michael, Atiyeh, Mazin, Gleich, Gerald, Walsh, Marie-Therese
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116188/
https://www.ncbi.nlm.nih.gov/pubmed/21686182
http://dx.doi.org/10.3390/ijms12053237