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S1P, dihydro-S1P and C24:1-ceramide levels in the HDL-containing fraction of serum inversely correlate with occurrence of ischemic heart disease

BACKGROUND: The lysosphingolipid sphingosine 1-phosphate (S1P) is carried in the blood in association with lipoproteins, predominantly high density lipoproteins (HDL). Emerging evidence suggests that many of the effects of HDL on cardiovascular function may be attributable to its S1P cargo. METHODS:...

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Detalles Bibliográficos
Autores principales: Argraves, Kelley M, Sethi, Amar A, Gazzolo, Patrick J, Wilkerson, Brent A, Remaley, Alan T, Tybjaerg-Hansen, Anne, Nordestgaard, Børge G, Yeatts, Sharon D, Nicholas, Katherine S, Barth, Jeremy L, Argraves, W Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116499/
https://www.ncbi.nlm.nih.gov/pubmed/21554699
http://dx.doi.org/10.1186/1476-511X-10-70