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Human Motor Neuron Progenitor Transplantation Leads to Endogenous Neuronal Sparing in 3 Models of Motor Neuron Loss

Motor neuron loss is characteristic of many neurodegenerative disorders and results in rapid loss of muscle control, paralysis, and eventual death in severe cases. In order to investigate the neurotrophic effects of a motor neuron lineage graft, we transplanted human embryonic stem cell-derived moto...

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Detalles Bibliográficos
Autores principales: Wyatt, Tanya J., Rossi, Sharyn L., Siegenthaler, Monica M., Frame, Jennifer, Robles, Rockelle, Nistor, Gabriel, Keirstead, Hans S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116523/
https://www.ncbi.nlm.nih.gov/pubmed/21716648
http://dx.doi.org/10.4061/2011/207230