Cargando…

Human Motor Neuron Progenitor Transplantation Leads to Endogenous Neuronal Sparing in 3 Models of Motor Neuron Loss

Motor neuron loss is characteristic of many neurodegenerative disorders and results in rapid loss of muscle control, paralysis, and eventual death in severe cases. In order to investigate the neurotrophic effects of a motor neuron lineage graft, we transplanted human embryonic stem cell-derived moto...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wyatt, Tanya J., Rossi, Sharyn L., Siegenthaler, Monica M., Frame, Jennifer, Robles, Rockelle, Nistor, Gabriel, Keirstead, Hans S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE-Hindawi Access to Research 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116523/ https://www.ncbi.nlm.nih.gov/pubmed/21716648 http://dx.doi.org/10.4061/2011/207230

Ejemplares similares

Histological and Functional Benefit Following Transplantation of Motor Neuron Progenitors to the Injured Rat Spinal Cord
por: Rossi, Sharyn L., et al.
Publicado: (2010)

Derivation of High Purity Neuronal Progenitors from Human Embryonic Stem Cells
por: Nistor, Gabriel, et al.
Publicado: (2011)

A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells
por: Cutarelli, Alessandro, et al.
Publicado: (2021)

Generation and characterization of motor neuron progenitors and motor neurons using metachromatic leukodystrophy-induced pluripotent stem cells
por: Hossain, Mohammad Arif, et al.
Publicado: (2022)

Motor neurons and the generation of spinal motor neuron diversity
por: Stifani, Nicolas
Publicado: (2014)

Protein Arginine Methyltransferase 1 Ablation in Motor Neurons Causes Mitochondrial Dysfunction Leading to Age-related Motor Neuron Degeneration with Muscle Loss
por: So, Hyun-Kyung, et al.
Publicado: (2023)

PuraMatrix hydrogel enhances the expression of motor neuron progenitor marker and improves adhesion and proliferation of motor neuron-like cells
por: Darvishi, Marzieh, et al.
Publicado: (2020)

Heavy metals in locus ceruleus and motor neurons in motor neuron disease
por: Pamphlett, Roger, et al.
Publicado: (2013)

Remyelination, axonal sparing, and locomotor recovery following transplantation of glial-committed progenitor cells into the MHV model of multiple sclerosis
por: Totoiu, Minodora O., et al.
Publicado: (2004)

Prenatal Octamethylcyclotetrasiloxane Exposure Impaired Proliferation of Neuronal Progenitor, Leading to Motor, Cognition, Social and Behavioral Functions
por: Tran, Dinh Nam, et al.
Publicado: (2021)

Communications Technology and Motor Neuron Disease: An Australian Survey of People With Motor Neuron Disease
por: Mackenzie, Lynette, et al.
Publicado: (2016)

Neuroinflammation in motor neuron disease
por: Komine, Okiru, et al.
Publicado: (2015)

The lower motor neuron homunculus
por: Ravits, John, et al.
Publicado: (2022)

Reprogramming astrocytes to motor neurons by activation of endogenous Ngn2 and Isl1
por: Zhou, Meiling, et al.
Publicado: (2021)

Transport and Secretion of the Wnt3 Ligand by Motor Neuron-like Cells and Developing Motor Neurons
por: Pinto, Cristina, et al.
Publicado: (2021)

Cerebellospinal Neurons Regulate Motor Performance and Motor Learning
por: Sathyamurthy, Anupama, et al.
Publicado: (2020)

Motor neurons and oligodendrocytes arise from distinct cell lineages by progenitor recruitment
por: Ravanelli, Andrew M., et al.
Publicado: (2015)

α‐Motor neurons are spared from aging while their synaptic inputs degenerate in monkeys and mice
por: Maxwell, Nicholas, et al.
Publicado: (2018)

Strong neuron-to-body coupling implies weak neuron-to-neuron coupling in motor cortex
por: Kells, Patrick A., et al.
Publicado: (2019)

Lower Motor Neuron Findings after Upper Motor Neuron Injury: Insights from Postoperative Supplementary Motor Area Syndrome
por: Florman, Jeffrey E., et al.
Publicado: (2013)

CSF Heavy Neurofilament May Discriminate and Predict Motor Neuron Diseases with Upper Motor Neuron Involvement
por: Simonini, Cecilia, et al.
Publicado: (2021)

Altered excitability of motor neuron pathways after stroke: more than upper motor neuron impairments
por: Li, Pingping, et al.
Publicado: (2022)

Loss of spatacsin function alters lysosomal lipid clearance leading to upper and lower motor neuron degeneration
por: Branchu, Julien, et al.
Publicado: (2017)

Injury-Associated PACAP Expression in Rat Sensory and Motor Neurons Is Induced by Endogenous BDNF
por: Pettersson, Lina M. E., et al.
Publicado: (2014)

Orofacial Apraxia in Motor Neuron Disease
por: Lobo, Patrícia Pita, et al.
Publicado: (2013)

Mimics and chameleons in motor neurone disease
por: Turner, Martin R, et al.
Publicado: (2013)

Multidisciplinary Interventions in Motor Neuron Disease
por: Williams, U. E., et al.
Publicado: (2014)

Allgrove syndrome and motor neuron disease
por: de Freitas, Marcos R.G., et al.
Publicado: (2018)

Motor Neuron Susceptibility in ALS/FTD
por: Ragagnin, Audrey M. G., et al.
Publicado: (2019)

Differentiating lower motor neuron syndromes
por: Garg, Nidhi, et al.
Publicado: (2017)

Genetic testing in motor neurone disease
por: Dharmadasa, Thanuja, et al.
Publicado: (2022)

Correction to: The lower motor neuron homunculus
Publicado: (2022)

Motor Neuron Disease and Its Management
por: Parton, Matthew J, et al.
Publicado: (1999)

Progranulin is expressed within motor neurons and promotes neuronal cell survival
por: Ryan, Cara L, et al.
Publicado: (2009)

Visualization of Sensory Neurons and Their Projections in an Upper Motor Neuron Reporter Line
por: Genç, Barış, et al.
Publicado: (2015)

Motor Neuron Diseases and Neuroprotective Peptides: A Closer Look to Neurons
por: Zuccaro, Emanuela, et al.
Publicado: (2021)

Jagged2 controls the generation of motor neuron and oligodendrocyte progenitors in the ventral spinal cord
por: Rabadán, M A, et al.
Publicado: (2012)

Selected statins produce rapid spinal motor neuron loss in vitro
por: Murinson, Beth B, et al.
Publicado: (2012)

Mitigating Motor Neuronal Loss in C. elegans Model of ALS8
por: Zhang, Wendy, et al.
Publicado: (2017)

Beta-band intermuscular coherence: a novel biomarker of upper motor neuron dysfunction in motor neuron disease
por: Fisher, Karen M., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_sgdaf24ct02ihb7r7ouur66v9k