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Variability in Estrogen-Metabolizing Genes and Their Association with Genomic Instability in Untreated Breast Cancer Patients and Healthy Women

In the present study, we investigated the relationship between polymorphisms in the estrogen-metabolizing genes CYP17, CYP1B1, CYP1A1, and COMT and genomic instability in the peripheral blood lymphocytes of 62 BC patients and 62 controls considering that increased or prolonged exposure to estrogen c...

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Detalles Bibliográficos
Autores principales: Alves dos Santos, Raquel, Teixeira, Ana Cláudia, Mayorano, Mônica Beatriz, Carrara, Hélio Humberto Angotti, Moreira de Andrade, Jurandyr, Takahashi, Catarina Satie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116633/
https://www.ncbi.nlm.nih.gov/pubmed/21716904
http://dx.doi.org/10.1155/2011/571784