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Variability in Estrogen-Metabolizing Genes and Their Association with Genomic Instability in Untreated Breast Cancer Patients and Healthy Women
In the present study, we investigated the relationship between polymorphisms in the estrogen-metabolizing genes CYP17, CYP1B1, CYP1A1, and COMT and genomic instability in the peripheral blood lymphocytes of 62 BC patients and 62 controls considering that increased or prolonged exposure to estrogen c...
Autores principales: | Alves dos Santos, Raquel, Teixeira, Ana Cláudia, Mayorano, Mônica Beatriz, Carrara, Hélio Humberto Angotti, Moreira de Andrade, Jurandyr, Takahashi, Catarina Satie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116633/ https://www.ncbi.nlm.nih.gov/pubmed/21716904 http://dx.doi.org/10.1155/2011/571784 |
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