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TLR2 Signaling Contributes to Rapid Inflammasome Activation during F. novicida Infection

BACKGROUND: Early detection of microorganisms by the innate immune system is provided by surface-expressed and endosomal pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs). Detection of microbial components by TLRs initiates a signaling cascade leading to the expression of proin...

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Detalles Bibliográficos
Autores principales: Jones, Crystal L., Weiss, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116832/
https://www.ncbi.nlm.nih.gov/pubmed/21698237
http://dx.doi.org/10.1371/journal.pone.0020609