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Clinical-Grade Generation of Active NK Cells from Cord Blood Hematopoietic Progenitor Cells for Immunotherapy Using a Closed-System Culture Process

Natural killer (NK) cell-based adoptive immunotherapy is a promising treatment approach for many cancers. However, development of protocols that provide large numbers of functional NK cells produced under GMP conditions are required to facilitate clinical studies. In this study, we translated our cy...

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Detalles Bibliográficos
Autores principales: Spanholtz, Jan, Preijers, Frank, Tordoir, Marleen, Trilsbeek, Carel, Paardekooper, Jos, de Witte, Theo, Schaap, Nicolaas, Dolstra, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116834/
https://www.ncbi.nlm.nih.gov/pubmed/21698239
http://dx.doi.org/10.1371/journal.pone.0020740