Disruption of LRRK2 Does Not Cause Specific Loss of Dopaminergic Neurons in Zebrafish

Mutations in LRRK2 are genetically linked to Parkinson's disease (PD) but its normal biological function is largely unknown. Sheng et al. recently reported that deletion of the WD40 domain of LRRK2 in zebrafish specifically causes PD-like loss of neurons and behavior defect. However, our simila...

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Detalles Bibliográficos
Autores principales: Ren, Guiqi, Xin, Shengchang, Li, Song, Zhong, Hanbing, Lin, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116841/
https://www.ncbi.nlm.nih.gov/pubmed/21698186
http://dx.doi.org/10.1371/journal.pone.0020630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116841/
https://www.ncbi.nlm.nih.gov/pubmed/21698186
http://dx.doi.org/10.1371/journal.pone.0020630

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