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Disruption of LRRK2 Does Not Cause Specific Loss of Dopaminergic Neurons in Zebrafish
Mutations in LRRK2 are genetically linked to Parkinson's disease (PD) but its normal biological function is largely unknown. Sheng et al. recently reported that deletion of the WD40 domain of LRRK2 in zebrafish specifically causes PD-like loss of neurons and behavior defect. However, our simila...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116841/ https://www.ncbi.nlm.nih.gov/pubmed/21698186 http://dx.doi.org/10.1371/journal.pone.0020630 |