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Predicting Protein Folds with Fold-Specific PSSM Libraries

Accurately assigning folds for divergent protein sequences is a major obstacle to structural studies. Herein, we outline an effective method for fold recognition using sets of PSSMs, each of which is constructed for different protein folds. Our analyses demonstrate that FSL (Fold-specific Position S...

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Detalles Bibliográficos
Autores principales: Hong, Yoojin, Chintapalli, Sree Vamsee, Ko, Kyung Dae, Bhardwaj, Gaurav, Zhang, Zhenhai, van Rossum, Damian, Patterson, Randen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116844/
https://www.ncbi.nlm.nih.gov/pubmed/21698189
http://dx.doi.org/10.1371/journal.pone.0020557