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ER Stress Induces Anabolic Resistance in Muscle Cells through PKB-Induced Blockade of mTORC1

BACKGROUND: Anabolic resistance is the inability to increase protein synthesis in response to an increase in amino acids following a meal. One potential mediator of anabolic resistance is endoplasmic reticulum (ER) stress. The purpose of the present study was to test whether ER stress impairs the re...

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Detalles Bibliográficos
Autores principales: Deldicque, Louise, Bertrand, Luc, Patton, Amy, Francaux, Marc, Baar, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116857/
https://www.ncbi.nlm.nih.gov/pubmed/21698202
http://dx.doi.org/10.1371/journal.pone.0020993