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Dynamics of Antibiotic Resistant Mycobacterium tuberculosis during Long-Term Infection and Antibiotic Treatment

For an infecting bacterium the human body provides several potential ecological niches with both internally (e.g. host immunity) and externally (e.g. antibiotic use) imposed growth restrictions that are expected to drive adaptive evolution in the bacterium, including the development of antibiotic re...

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Detalles Bibliográficos
Autores principales: Mariam, Solomon H., Werngren, Jim, Aronsson, Joakim, Hoffner, Sven, Andersson, Dan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116863/
https://www.ncbi.nlm.nih.gov/pubmed/21698208
http://dx.doi.org/10.1371/journal.pone.0021147