Proximity of Transmembrane Segments 5 and 8 of the Glutamate Transporter GLT-1 Inferred from Paired Cysteine Mutagenesis

BACKGROUND: GLT-1 is a glial glutamate transporter which maintains low synaptic concentrations of the excitatory neurotransmitter enabling efficient synaptic transmission. Based on the crystal structure of the bacterial homologue Glt(Ph), it has been proposed that the reentrant loop HP2, which conne...

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Detalles Bibliográficos
Autores principales: Zhang, Xiuping, Qu, Shaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116888/
https://www.ncbi.nlm.nih.gov/pubmed/21698173
http://dx.doi.org/10.1371/journal.pone.0021288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116888/
https://www.ncbi.nlm.nih.gov/pubmed/21698173
http://dx.doi.org/10.1371/journal.pone.0021288

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