Quinpramine Ameliorates Rat Experimental Autoimmune Neuritis and Redistributes MHC Class II Molecules

Activation of inflammatory cells is central to the pathogenesis of autoimmune demyelinating diseases of the peripheral nervous system. The novel chimeric compound quinpramine—generated from imipramine and quinacrine—redistributes cholesterol rich membrane domains to intracellular compartments. We st...

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Detalles Bibliográficos
Autores principales: Meyer zu Hörste, Gerd, Mausberg, Anne K., Müller, Johanna I., Lehmann, Helmar C., Löber, Stefan, Gmeiner, Peter, Hartung, Hans-Peter, Stüve, Olaf, Korth, Carsten, Kieseier, Bernd C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116892/
https://www.ncbi.nlm.nih.gov/pubmed/21698177
http://dx.doi.org/10.1371/journal.pone.0021223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116892/
https://www.ncbi.nlm.nih.gov/pubmed/21698177
http://dx.doi.org/10.1371/journal.pone.0021223

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