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The Role of Response Elements Organization in Transcription Factor Selectivity: The IFN-β Enhanceosome Example
What is the mechanism through which transcription factors (TFs) assemble specifically along the enhancer DNA? The IFN-β enhanceosome provides a good model system: it is small; its components' crystal structures are available; and there are biochemical and cellular data. In the IFN-β enhanceosom...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116919/ https://www.ncbi.nlm.nih.gov/pubmed/21698143 http://dx.doi.org/10.1371/journal.pcbi.1002077 |