Genetic regulation of the ramA locus and its expression in clinical isolates of Klebsiella pneumoniae

Tigecycline resistance has been attributed to ramA overexpression and subsequent acrA upregulation. The ramA locus, originally identified in Klebsiella pneumoniae, has homologues in Enterobacter and Salmonella spp. In this study, we identify in silico that the ramR binding site is also present in Ci...

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Detalles Bibliográficos
Autores principales: Rosenblum, R., Khan, E., Gonzalez, G., Hasan, R., Schneiders, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117140/
https://www.ncbi.nlm.nih.gov/pubmed/21514798
http://dx.doi.org/10.1016/j.ijantimicag.2011.02.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117140/
https://www.ncbi.nlm.nih.gov/pubmed/21514798
http://dx.doi.org/10.1016/j.ijantimicag.2011.02.012

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