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Genetic regulation of the ramA locus and its expression in clinical isolates of Klebsiella pneumoniae
Tigecycline resistance has been attributed to ramA overexpression and subsequent acrA upregulation. The ramA locus, originally identified in Klebsiella pneumoniae, has homologues in Enterobacter and Salmonella spp. In this study, we identify in silico that the ramR binding site is also present in Ci...
Autores principales: | Rosenblum, R., Khan, E., Gonzalez, G., Hasan, R., Schneiders, T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Publishers
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117140/ https://www.ncbi.nlm.nih.gov/pubmed/21514798 http://dx.doi.org/10.1016/j.ijantimicag.2011.02.012 |
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