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Uncover disease genes by maximizing information flow in the phenome–interactome network
Motivation: Pinpointing genes that underlie human inherited diseases among candidate genes in susceptibility genetic regions is the primary step towards the understanding of pathogenesis of diseases. Although several probabilistic models have been proposed to prioritize candidate genes using phenoty...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117332/ https://www.ncbi.nlm.nih.gov/pubmed/21685067 http://dx.doi.org/10.1093/bioinformatics/btr213 |