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Characterization and improvement of RNA-Seq precision in quantitative transcript expression profiling

Motivation: Measurement precision determines the power of any analysis to reliably identify significant signals, such as in screens for differential expression, independent of whether the experimental design incorporates replicates or not. With the compilation of large-scale RNA-Seq datasets with te...

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Detalles Bibliográficos
Autores principales: Łabaj, Paweł P., Leparc, Germán G., Linggi, Bryan E., Markillie, Lye Meng, Wiley, H. Steven, Kreil, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117338/
https://www.ncbi.nlm.nih.gov/pubmed/21685096
http://dx.doi.org/10.1093/bioinformatics/btr247