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Predicting site-specific human selective pressure using evolutionary signatures

Motivation: The identification of non-coding functional regions of the human genome remains one of the main challenges of genomics. By observing how a given region evolved over time, one can detect signs of negative or positive selection hinting that the region may be functional. With the quickly in...

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Detalles Bibliográficos
Autores principales: Sadri, Javad, Diallo, Abdoulaye Banire, Blanchette, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117352/
https://www.ncbi.nlm.nih.gov/pubmed/21685080
http://dx.doi.org/10.1093/bioinformatics/btr241