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Predicting site-specific human selective pressure using evolutionary signatures
Motivation: The identification of non-coding functional regions of the human genome remains one of the main challenges of genomics. By observing how a given region evolved over time, one can detect signs of negative or positive selection hinting that the region may be functional. With the quickly in...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117352/ https://www.ncbi.nlm.nih.gov/pubmed/21685080 http://dx.doi.org/10.1093/bioinformatics/btr241 |