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Detecting epistatic effects in association studies at a genomic level based on an ensemble approach

Motivation: Most complex diseases involve multiple genes and their interactions. Although genome-wide association studies (GWAS) have shown some success for identifying genetic variants underlying complex diseases, most existing studies are based on limited single-locus approaches, which detect sing...

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Detalles Bibliográficos
Autores principales: Li, Jing, Horstman, Benjamin, Chen, Yixuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117367/
https://www.ncbi.nlm.nih.gov/pubmed/21685074
http://dx.doi.org/10.1093/bioinformatics/btr227