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Environment specific substitution tables improve membrane protein alignment

Motivation: Membrane proteins are both abundant and important in cells, but the small number of solved structures restricts our understanding of them. Here we consider whether membrane proteins undergo different substitutions from their soluble counterparts and whether these can be used to improve m...

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Detalles Bibliográficos
Autores principales: Hill, Jamie R., Kelm, Sebastian, Shi, Jiye, Deane, Charlotte M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117371/
https://www.ncbi.nlm.nih.gov/pubmed/21685065
http://dx.doi.org/10.1093/bioinformatics/btr230