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Sequence-based prediction of protein crystallization, purification and production propensity

Motivation: X-ray crystallography-based protein structure determination, which accounts for majority of solved structures, is characterized by relatively low success rates. One solution is to build tools which support selection of targets that are more likely to crystallize. Several in silico method...

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Detalles Bibliográficos
Autores principales: Mizianty, Marcin J., Kurgan, Lukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117383/
https://www.ncbi.nlm.nih.gov/pubmed/21685077
http://dx.doi.org/10.1093/bioinformatics/btr229