An enhanced Petri-net model to predict synergistic effects of pairwise drug combinations from gene microarray data

Motivation: Prediction of synergistic effects of drug combinations has traditionally been relied on phenotypic response data. However, such methods cannot be used to identify molecular signaling mechanisms of synergistic drug combinations. In this article, we propose an enhanced Petri-Net (EPN) mode...

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Detalles Bibliográficos
Autores principales: Jin, Guangxu, Zhao, Hong, Zhou, Xiaobo, Wong, Stephen T. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Ismb/Eccb 2011 Proceedings Papers Committee July 17 to July 19, 2011, Vienna, Austria
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117391/
https://www.ncbi.nlm.nih.gov/pubmed/21685086
http://dx.doi.org/10.1093/bioinformatics/btr202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117391/
https://www.ncbi.nlm.nih.gov/pubmed/21685086
http://dx.doi.org/10.1093/bioinformatics/btr202

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