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From sets to graphs: towards a realistic enrichment analysis of transcriptomic systems

Motivation: Current gene set enrichment approaches do not take interactions and associations between set members into account. Mutual activation and inhibition causing positive and negative correlation among set members are thus neglected. As a consequence, inconsistent regulations and contextless e...

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Detalles Bibliográficos
Autores principales: Geistlinger, Ludwig, Csaba, Gergely, Küffner, Robert, Mulder, Nicola, Zimmer, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117393/
https://www.ncbi.nlm.nih.gov/pubmed/21685094
http://dx.doi.org/10.1093/bioinformatics/btr228