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Assessment of replicate bias in 454 pyrosequencing and a multi-purpose read-filtering tool

BACKGROUND: Roche 454 pyrosequencing platform is often considered the most versatile of the Next Generation Sequencing technology platforms, permitting the sequencing of large genomes, the analysis of variations or the study of transcriptomes. A recent reported bias leads to the production of multip...

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Detalles Bibliográficos
Autores principales: Jérôme, Mariette, Noirot, Céline, Klopp, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117718/
https://www.ncbi.nlm.nih.gov/pubmed/21615897
http://dx.doi.org/10.1186/1756-0500-4-149