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Assessment of replicate bias in 454 pyrosequencing and a multi-purpose read-filtering tool
BACKGROUND: Roche 454 pyrosequencing platform is often considered the most versatile of the Next Generation Sequencing technology platforms, permitting the sequencing of large genomes, the analysis of variations or the study of transcriptomes. A recent reported bias leads to the production of multip...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117718/ https://www.ncbi.nlm.nih.gov/pubmed/21615897 http://dx.doi.org/10.1186/1756-0500-4-149 |