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Increased IL-10 mRNA expression in tumor-associated macrophage correlated with late stage of lung cancer

BACKGROUND: Monocyte recruited into the tumor and maturation to tumor-associated macrophage (TAM). Interleukin-10(IL-10) is a potent immunosuppressive cytokine, which can be secreted from both primary tumor and stromal cells. However, there are controversies regarding its role in the progression of...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Lu, Meng, Zhang, Jie, Chen, Sufeng, Luo, Xiaoyang, Qin, Ying, Chen, Haiquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117740/
https://www.ncbi.nlm.nih.gov/pubmed/21595995
http://dx.doi.org/10.1186/1756-9966-30-62