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A hepatoprotective Lindera obtusiloba extract suppresses growth and attenuates insulin like growth factor-1 receptor signaling and NF-kappaB activity in human liver cancer cell lines

BACKGROUND: In traditional Chinese and Korean medicine, an aqueous extract derived from wood and bark of the Japanese spice bush Lindera obtusiloba (L.obtusiloba) is applied to treat inflammations and chronic liver diseases including hepatocellular carcinoma. We previously demonstrated anti-fibrotic...

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Detalles Bibliográficos
Autores principales: Freise, Christian, Ruehl, Martin, Erben, Ulrike, Neumann, Ulf, Seehofer, Daniel, Kim, Ki Young, Trowitzsch-Kienast, Wolfram, Stroh, Thorsten, Zeitz, Martin, Somasundaram, Rajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117754/
https://www.ncbi.nlm.nih.gov/pubmed/21569410
http://dx.doi.org/10.1186/1472-6882-11-39