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Up-Regulated Dicer Expression in Patients with Cutaneous Melanoma

BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNAs (18–24 nucleotides) that have recently been shown to regulate gene expression during cancer progression. Dicer, a central enzyme in the multi-component miRNA biogenesis pathway, is involved in cutting precursor miRNAs to functionally mature fo...

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Detalles Bibliográficos
Autores principales: Ma, Zhihai, Swede, Helen, Cassarino, David, Fleming, Elizabeth, Fire, Andrew, Dadras, Soheil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117784/
https://www.ncbi.nlm.nih.gov/pubmed/21698147
http://dx.doi.org/10.1371/journal.pone.0020494