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Hydrogen Bonding Penalty upon Ligand Binding

Ligand binding involves breakage of hydrogen bonds with water molecules and formation of new hydrogen bonds between protein and ligand. In this work, the change of hydrogen bonding energy in the binding process, namely hydrogen bonding penalty, is evaluated with a new method. The hydrogen bonding pe...

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Detalles Bibliográficos
Autores principales: Zhao, Hongtao, Huang, Danzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117785/
https://www.ncbi.nlm.nih.gov/pubmed/21698148
http://dx.doi.org/10.1371/journal.pone.0019923