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Beyond DNA binding - a review of the potential mechanisms mediating quinacrine's therapeutic activities in parasitic infections, inflammation, and cancers

This is an in-depth review of the history of quinacrine as well as its pharmacokinetic properties and established record of safety as an FDA-approved drug. The potential uses of quinacrine as an anti-cancer agent are discussed with particular attention to its actions on nuclear proteins, the arachid...

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Detalles Bibliográficos
Autores principales: Ehsanian, Reza, Van Waes, Carter, Feller , Stephan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117821/
https://www.ncbi.nlm.nih.gov/pubmed/21569639
http://dx.doi.org/10.1186/1478-811X-9-13