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Defective interfering virus protects elderly mice from influenza

BACKGROUND: We have identified and characterised a defective-interfering (DI) influenza A virus particles containing a highly deleted segment 1 RNA that has broad-spectrum antiviral activity. In young adult mice it exerts protection against several different subtypes of influenza A virus (defined he...

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Detalles Bibliográficos
Autores principales: Scott, Paul D, Meng, Bo, Marriott, Anthony C, Easton, Andrew J, Dimmock, Nigel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117841/
https://www.ncbi.nlm.nih.gov/pubmed/21549019
http://dx.doi.org/10.1186/1743-422X-8-212