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A novel candidate HIV vaccine vector based on the replication deficient Capripoxvirus, Lumpy skin disease virus (LSDV)

BACKGROUND: The Capripoxvirus, Lumpy skin disease virus (LSDV) has a restricted host-range and is being investigated as a novel HIV-1 vaccine vector. LSDV does not complete its replication cycle in non-ruminant hosts. METHODS: The safety of LSDV was tested at doses of 10(4 )and 10(6 )plaque forming...

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Detalles Bibliográficos
Autores principales: Shen, Yen-Ju, Shephard, Enid, Douglass, Nicola, Johnston, Nicolette, Adams, Craig, Williamson, Carolyn, Williamson, Anna-Lise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117847/
https://www.ncbi.nlm.nih.gov/pubmed/21624130
http://dx.doi.org/10.1186/1743-422X-8-265