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Analysis of Proteasomal Proteolysis during the In Vitro Metacyclogenesis of Trypanosoma cruzi

Proteasomes are large protein complexes, whose main function is to degrade unnecessary or damaged proteins. The inhibition of proteasome activity in Trypanosoma cruzi blocks parasite replication and cellular differentiation. We demonstrate that proteasome-dependent proteolysis occurs during the cell...

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Detalles Bibliográficos
Autores principales: Cardoso, Josiane, Lima, Carla De Paula, Leal, Tiago, Gradia, Daniela F., Fragoso, Stênio P., Goldenberg, Samuel, De Sá, Renata Guerra, Krieger, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117861/
https://www.ncbi.nlm.nih.gov/pubmed/21698116
http://dx.doi.org/10.1371/journal.pone.0021027