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MIP/Aquaporin 0 Represents a Direct Transcriptional Target of PITX3 in the Developing Lens
The PITX3 bicoid-type homeodomain transcription factor plays an important role in lens development in vertebrates. PITX3 deficiency results in a spectrum of phenotypes from isolated cataracts to microphthalmia in humans, and lens degeneration in mice and zebrafish. While identification of downstream...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117865/ https://www.ncbi.nlm.nih.gov/pubmed/21698120 http://dx.doi.org/10.1371/journal.pone.0021122 |