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MIP/Aquaporin 0 Represents a Direct Transcriptional Target of PITX3 in the Developing Lens

The PITX3 bicoid-type homeodomain transcription factor plays an important role in lens development in vertebrates. PITX3 deficiency results in a spectrum of phenotypes from isolated cataracts to microphthalmia in humans, and lens degeneration in mice and zebrafish. While identification of downstream...

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Detalles Bibliográficos
Autores principales:	Sorokina, Elena A., Muheisen, Sanaa, Mlodik, Nevin, Semina, Elena V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117865/ https://www.ncbi.nlm.nih.gov/pubmed/21698120 http://dx.doi.org/10.1371/journal.pone.0021122

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