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PEDF Regulates Vascular Permeability by a γ-Secretase-Mediated Pathway

Increased vascular permeability is an inciting event in many vascular complications including diabetic retinopathy. We have previously reported that pigment epithelium-derived factor (PEDF) is able to inhibit vascular endothelial growth factor (VEGF)-induced angiogenesis through a novel γ-secretase-...

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Detalles Bibliográficos
Autores principales: Cai, Jun, Wu, Lin, Qi, Xiaoping, Li Calzi, Sergio, Caballero, Sergio, Shaw, Lynn, Ruan, Qing, Grant, Maria B., Boulton, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117873/
https://www.ncbi.nlm.nih.gov/pubmed/21695048
http://dx.doi.org/10.1371/journal.pone.0021164