The Ubiquitin-Like Protein PLIC-1 or Ubiquilin 1 Inhibits TLR3-Trif Signaling

BACKGROUND: The innate immune responses to virus infection are initiated by either Toll-like receptors (TLR3/7/8/9) or cytoplasmic double-stranded RNA (dsRNA)-recognizing RNA helicases RIG-I and MDA5. To avoid causing injury to the host, these signaling pathways must be switched off in time by negat...

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Detalles Bibliográficos
Autores principales: Biswas, Nabanita, Liu, Shufeng, Ronni, Tapani, Aussenberg, Steven E., Liu, Weiqun, Fujita, Takashi, Wang, Tianyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117881/
https://www.ncbi.nlm.nih.gov/pubmed/21695056
http://dx.doi.org/10.1371/journal.pone.0021153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117881/
https://www.ncbi.nlm.nih.gov/pubmed/21695056
http://dx.doi.org/10.1371/journal.pone.0021153

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