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Molecular mechanisms underlying the control of antigenic variation in African trypanosomes

African trypanosomes escape the host adaptive immune response by switching their dense protective coat of Variant Surface Glycoprotein (VSG). Each cell expresses only one VSG gene at a time from a telomeric expression site (ES). The ‘pre-genomic’ era saw the identification of the range of pathways i...

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Detalles Bibliográficos
Autores principales: Horn, David, McCulloch, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Current Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117991/
https://www.ncbi.nlm.nih.gov/pubmed/20884281
http://dx.doi.org/10.1016/j.mib.2010.08.009